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E. coli JM83 damages the mucosal barrier in Ednrb knockout mice to promote the development of Hirschsprung-associated enterocolitis via activation of TLR4/p-p38/NF-κB signaling

Hirschsprung-associated enterocolitis (HAEC) is characterized by intestinal mucosal damage and an imbalance in the intestinal microbiota. Recent studies have indicated that the TLR4/p-p38/NF-κB signaling pathway in the intestine is of great importance to intestinal mucosal integrity. The present stu...

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Detalles Bibliográficos
Autores principales: Zheng, Zebing, Gao, Mingjuan, Tang, Chengyan, Huang, Lu, Gong, Yuan, Liu, Yuanmei, Wang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971921/
https://www.ncbi.nlm.nih.gov/pubmed/35302172
http://dx.doi.org/10.3892/mmr.2022.12684

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