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E. coli JM83 damages the mucosal barrier in Ednrb knockout mice to promote the development of Hirschsprung-associated enterocolitis via activation of TLR4/p-p38/NF-κB signaling
Hirschsprung-associated enterocolitis (HAEC) is characterized by intestinal mucosal damage and an imbalance in the intestinal microbiota. Recent studies have indicated that the TLR4/p-p38/NF-κB signaling pathway in the intestine is of great importance to intestinal mucosal integrity. The present stu...
Autores principales: | Zheng, Zebing, Gao, Mingjuan, Tang, Chengyan, Huang, Lu, Gong, Yuan, Liu, Yuanmei, Wang, Jian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971921/ https://www.ncbi.nlm.nih.gov/pubmed/35302172 http://dx.doi.org/10.3892/mmr.2022.12684 |
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