High-resolution Slide-seqV2 spatial transcriptomics enables discovery of disease-specific cell neighborhoods and pathways

High-resolution spatial transcriptomics enables mapping of RNA expression directly from intact tissue sections; however, its utility for the elucidation of disease processes and therapeutically actionable pathways remains unexplored. We applied Slide-seqV2 to mouse and human kidneys, in healthy and...

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Detalles Bibliográficos
Autores principales: Marshall, Jamie L., Noel, Teia, Wang, Qingbo S., Chen, Haiqi, Murray, Evan, Subramanian, Ayshwarya, Vernon, Katherine A., Bazua-Valenti, Silvana, Liguori, Katie, Keller, Keith, Stickels, Robert R., McBean, Breanna, Heneghan, Rowan M., Weins, Astrid, Macosko, Evan Z., Chen, Fei, Greka, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971939/
https://www.ncbi.nlm.nih.gov/pubmed/35372810
http://dx.doi.org/10.1016/j.isci.2022.104097

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