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Comparisons of α2-Adrenergic Agents, Medetomidine and Xylazine, with Pentobarbital for Anesthesia: Important Pitfalls in Diabetic and Nondiabetic Rats

PURPOSE: Anesthesia is necessary to conduct rodent electroretinograms (ERGs). We evaluated utility of the α2-agonist medetomidine versus xylazine for ERG studies in nondiabetic and diabetic rats. Pentobarbital was included as a comparator. METHODS: Male Sprague–Dawley rats, with and without streptoz...

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Detalles Bibliográficos
Autores principales:	Connell, Anna R., Hookham, Michelle B., Fu, Dongxu, Brazil, Derek P., Lyons, Timothy J., Yu, Jeremy Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2022
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8971989/ https://www.ncbi.nlm.nih.gov/pubmed/34964655 http://dx.doi.org/10.1089/jop.2021.0084

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