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Neurofilament Light Chain (NF-L) Stimulates Lipid Peroxidation to Neuronal Membrane through Microglia-Derived Ferritin Heavy Chain (FTH) Secretion

A part of the axonal cytoskeleton protein complex, neurofilament light chain (NF-L) has been suggested as a pathological hallmark in various neurological disorders, including hemorrhagic stroke, vascular dementia, and cerebral small vessel disease. Neuroaxonal debris are mainly engulfed and phagocyt...

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Detalles Bibliográficos
Autores principales: Gong, Li, Yu, Qiuyue, Wang, Haichao, Xu, Chenhaoyi, Dou, Yunxiao, Mao, Bingjie, Zhao, Yanxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972155/
https://www.ncbi.nlm.nih.gov/pubmed/35368870
http://dx.doi.org/10.1155/2022/3938940