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Neurofilament Light Chain (NF-L) Stimulates Lipid Peroxidation to Neuronal Membrane through Microglia-Derived Ferritin Heavy Chain (FTH) Secretion
A part of the axonal cytoskeleton protein complex, neurofilament light chain (NF-L) has been suggested as a pathological hallmark in various neurological disorders, including hemorrhagic stroke, vascular dementia, and cerebral small vessel disease. Neuroaxonal debris are mainly engulfed and phagocyt...
Autores principales: | Gong, Li, Yu, Qiuyue, Wang, Haichao, Xu, Chenhaoyi, Dou, Yunxiao, Mao, Bingjie, Zhao, Yanxin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972155/ https://www.ncbi.nlm.nih.gov/pubmed/35368870 http://dx.doi.org/10.1155/2022/3938940 |
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