Cargando…

Fetal Organ Anomaly Classification Network for Identifying Organ Anomalies in Fetal MRI

Rapid development in Magnetic Resonance Imaging (MRI) has played a key role in prenatal diagnosis over the last few years. Deep learning (DL) architectures can facilitate the process of anomaly detection and affected-organ classification, making diagnosis more accurate and observer-independent. We p...

Descripción completa

Detalles Bibliográficos
Autores principales: Lo, Justin, Lim, Adam, Wagner, Matthias W., Ertl-Wagner, Birgit, Sussman, Dafna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972161/
https://www.ncbi.nlm.nih.gov/pubmed/35372832
http://dx.doi.org/10.3389/frai.2022.832485
_version_ 1784679783773241344
author Lo, Justin
Lim, Adam
Wagner, Matthias W.
Ertl-Wagner, Birgit
Sussman, Dafna
author_facet Lo, Justin
Lim, Adam
Wagner, Matthias W.
Ertl-Wagner, Birgit
Sussman, Dafna
author_sort Lo, Justin
collection PubMed
description Rapid development in Magnetic Resonance Imaging (MRI) has played a key role in prenatal diagnosis over the last few years. Deep learning (DL) architectures can facilitate the process of anomaly detection and affected-organ classification, making diagnosis more accurate and observer-independent. We propose a novel DL image classification architecture, Fetal Organ Anomaly Classification Network (FOAC-Net), which uses squeeze-and-excitation (SE) and naïve inception (NI) modules to automatically identify anomalies in fetal organs. This architecture can identify normal fetal anatomy, as well as detect anomalies present in the (1) brain, (2) spinal cord, and (3) heart. In this retrospective study, we included fetal 3-dimensional (3D) SSFP sequences of 36 participants. We classified the images on a slice-by-slice basis. FOAC-Net achieved a classification accuracy of 85.06, 85.27, 89.29, and 82.20% when predicting brain anomalies, no anomalies (normal), spinal cord anomalies, and heart anomalies, respectively. In a comparison study, FOAC-Net outperformed other state-of-the-art classification architectures in terms of class-average F1 and accuracy. This work aims to develop a novel classification architecture identifying the affected organs in fetal MRI.
format Online
Article
Text
id pubmed-8972161
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-89721612022-04-02 Fetal Organ Anomaly Classification Network for Identifying Organ Anomalies in Fetal MRI Lo, Justin Lim, Adam Wagner, Matthias W. Ertl-Wagner, Birgit Sussman, Dafna Front Artif Intell Artificial Intelligence Rapid development in Magnetic Resonance Imaging (MRI) has played a key role in prenatal diagnosis over the last few years. Deep learning (DL) architectures can facilitate the process of anomaly detection and affected-organ classification, making diagnosis more accurate and observer-independent. We propose a novel DL image classification architecture, Fetal Organ Anomaly Classification Network (FOAC-Net), which uses squeeze-and-excitation (SE) and naïve inception (NI) modules to automatically identify anomalies in fetal organs. This architecture can identify normal fetal anatomy, as well as detect anomalies present in the (1) brain, (2) spinal cord, and (3) heart. In this retrospective study, we included fetal 3-dimensional (3D) SSFP sequences of 36 participants. We classified the images on a slice-by-slice basis. FOAC-Net achieved a classification accuracy of 85.06, 85.27, 89.29, and 82.20% when predicting brain anomalies, no anomalies (normal), spinal cord anomalies, and heart anomalies, respectively. In a comparison study, FOAC-Net outperformed other state-of-the-art classification architectures in terms of class-average F1 and accuracy. This work aims to develop a novel classification architecture identifying the affected organs in fetal MRI. Frontiers Media S.A. 2022-03-18 /pmc/articles/PMC8972161/ /pubmed/35372832 http://dx.doi.org/10.3389/frai.2022.832485 Text en Copyright © 2022 Lo, Lim, Wagner, Ertl-Wagner and Sussman. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Artificial Intelligence
Lo, Justin
Lim, Adam
Wagner, Matthias W.
Ertl-Wagner, Birgit
Sussman, Dafna
Fetal Organ Anomaly Classification Network for Identifying Organ Anomalies in Fetal MRI
title Fetal Organ Anomaly Classification Network for Identifying Organ Anomalies in Fetal MRI
title_full Fetal Organ Anomaly Classification Network for Identifying Organ Anomalies in Fetal MRI
title_fullStr Fetal Organ Anomaly Classification Network for Identifying Organ Anomalies in Fetal MRI
title_full_unstemmed Fetal Organ Anomaly Classification Network for Identifying Organ Anomalies in Fetal MRI
title_short Fetal Organ Anomaly Classification Network for Identifying Organ Anomalies in Fetal MRI
title_sort fetal organ anomaly classification network for identifying organ anomalies in fetal mri
topic Artificial Intelligence
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972161/
https://www.ncbi.nlm.nih.gov/pubmed/35372832
http://dx.doi.org/10.3389/frai.2022.832485
work_keys_str_mv AT lojustin fetalorgananomalyclassificationnetworkforidentifyingorgananomaliesinfetalmri
AT limadam fetalorgananomalyclassificationnetworkforidentifyingorgananomaliesinfetalmri
AT wagnermatthiasw fetalorgananomalyclassificationnetworkforidentifyingorgananomaliesinfetalmri
AT ertlwagnerbirgit fetalorgananomalyclassificationnetworkforidentifyingorgananomaliesinfetalmri
AT sussmandafna fetalorgananomalyclassificationnetworkforidentifyingorgananomaliesinfetalmri