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Durable Response of Dabrafenib, Trametinib, and Capmatinib in an NSCLC Patient With Co-Existing BRAF-KIAA1549 Fusion and MET Amplification: A Case Report
BRAF fusions are rare driver oncogenes in non-small cell lung cancer (NSCLC). Similar with BRAF V600E mutation, it could also activate the MAPK signaling pathway. There are a few case reports which had indicated the potential response to BRAF inhibitors and its important role as de novo driver mutat...
Autores principales: | Chou, Yun-Tse, Lin, Chien-Chung, Lee, Chung-Ta, Pavlick, Dean C., Su, Po-Lan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972191/ https://www.ncbi.nlm.nih.gov/pubmed/35372088 http://dx.doi.org/10.3389/fonc.2022.838798 |
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