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lncRNA LINC00284 promotes nucleus pulposus cell proliferation and ECM synthesis via regulation of the miR-205-3p/Wnt/β-catenin axis
Intervertebral disc degeneration (IDD) is a leading cause of degenerative spinal disease. Long non-coding RNA (lncRNA) LINC00284 is overexpressed in multiple types of cancer and promotes cancer cell proliferation and inhibits apoptosis; however, its role in human IDD and nucleus pulposus (NP) remain...
Autores principales: | Zhu, Min, Yan, Xiaoling, Zhao, Yin, Xue, Huawei, Wang, Zhen, Wu, Bo, Li, Xiangyang, Shen, Yixin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972274/ https://www.ncbi.nlm.nih.gov/pubmed/35322864 http://dx.doi.org/10.3892/mmr.2022.12695 |
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