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Application of magnetic nanoparticles in cell therapy
Fe(3)O(4) magnetic nanoparticles (MNPs) are biomedical materials that have been approved by the FDA. To date, MNPs have been developed rapidly in nanomedicine and are of great significance. Stem cells and secretory vesicles can be used for tissue regeneration and repair. In cell therapy, MNPs which...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972776/ https://www.ncbi.nlm.nih.gov/pubmed/35365206 http://dx.doi.org/10.1186/s13287-022-02808-0 |
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author | Chen, Yuling Hou, Shike |
author_facet | Chen, Yuling Hou, Shike |
author_sort | Chen, Yuling |
collection | PubMed |
description | Fe(3)O(4) magnetic nanoparticles (MNPs) are biomedical materials that have been approved by the FDA. To date, MNPs have been developed rapidly in nanomedicine and are of great significance. Stem cells and secretory vesicles can be used for tissue regeneration and repair. In cell therapy, MNPs which interact with external magnetic field are introduced to achieve the purpose of cell directional enrichment, while MRI to monitor cell distribution and drug delivery. This paper reviews the size optimization, response in external magnetic field and biomedical application of MNPs in cell therapy and provides a comprehensive view. |
format | Online Article Text |
id | pubmed-8972776 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-89727762022-04-01 Application of magnetic nanoparticles in cell therapy Chen, Yuling Hou, Shike Stem Cell Res Ther Review Fe(3)O(4) magnetic nanoparticles (MNPs) are biomedical materials that have been approved by the FDA. To date, MNPs have been developed rapidly in nanomedicine and are of great significance. Stem cells and secretory vesicles can be used for tissue regeneration and repair. In cell therapy, MNPs which interact with external magnetic field are introduced to achieve the purpose of cell directional enrichment, while MRI to monitor cell distribution and drug delivery. This paper reviews the size optimization, response in external magnetic field and biomedical application of MNPs in cell therapy and provides a comprehensive view. BioMed Central 2022-04-01 /pmc/articles/PMC8972776/ /pubmed/35365206 http://dx.doi.org/10.1186/s13287-022-02808-0 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Review Chen, Yuling Hou, Shike Application of magnetic nanoparticles in cell therapy |
title | Application of magnetic nanoparticles in cell therapy |
title_full | Application of magnetic nanoparticles in cell therapy |
title_fullStr | Application of magnetic nanoparticles in cell therapy |
title_full_unstemmed | Application of magnetic nanoparticles in cell therapy |
title_short | Application of magnetic nanoparticles in cell therapy |
title_sort | application of magnetic nanoparticles in cell therapy |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972776/ https://www.ncbi.nlm.nih.gov/pubmed/35365206 http://dx.doi.org/10.1186/s13287-022-02808-0 |
work_keys_str_mv | AT chenyuling applicationofmagneticnanoparticlesincelltherapy AT houshike applicationofmagneticnanoparticlesincelltherapy |