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A multicenter phase II study on the efficacy and safety of hetrombopag in patients with severe aplastic anemia refractory to immunosuppressive therapy

BACKGROUND: In this single-arm phase II study (NCT03557099), we evaluated the efficacy and safety of hetrombopag, a small molecule thrombopoietin (TPO) receptor agonist, in patients with severe aplastic anemia (SAA) who were refractory to standard first-line immunosuppressive therapy (IST). METHODS:...

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Detalles Bibliográficos
Autores principales:	Peng, Guangxin, He, Guangsheng, Chang, Hong, Gao, Sujun, Liu, Xinjian, Chen, Tong, Li, Pei, Han, Bing, Miao, Miao, Ge, Zheng, Ge, Xiaoyan, Li, Fei, Li, Yingmei, Wang, Shunqing, Wang, Yi, Shen, Yaqi, Zhang, Tao, Zou, Jianjun, Zhang, Fengkui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972928/ https://www.ncbi.nlm.nih.gov/pubmed/35371427 http://dx.doi.org/10.1177/20406207221085197

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