Electrospray ionization of native membrane proteins proceeds via a charge equilibration step

Electrospray ionization mass spectrometry is increasingly applied to study the structures and interactions of membrane protein complexes. However, the charging mechanism is complicated by the presence of detergent micelles during ionization. Here, we show that the final charge of membrane proteins c...

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Detalles Bibliográficos
Autores principales: Yen, Hsin-Yung, Abramsson, Mia L., Agasid, Mark T., Lama, Dilraj, Gault, Joseph, Liko, Idlir, Kaldmäe, Margit, Saluri, Mihkel, Qureshi, Abdul Aziz, Suades, Albert, Drew, David, Degiacomi, Matteo T., Marklund, Erik G., Allison, Timothy M., Robinson, Carol V., Landreh, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8972943/
https://www.ncbi.nlm.nih.gov/pubmed/35424940
http://dx.doi.org/10.1039/d2ra01282k

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