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Histone methyltransferase Dot1L inhibits pancreatic cancer cell apoptosis by promoting NUPR1 expression

OBJECTIVE: To explore functions of the histone H3 lysine 79 (K79) methyltransferase Dot1L in the development of pancreatic cancer and evaluate the possibility of targeting Dot1L to inhibit pancreatic cancer progression. METHODS: Patient samples were used to detect differences in Dot1L expression bet...

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Detalles Bibliográficos
Autores principales:	Shan, Lin, Hao, Chen, Jun, Zheng, Qinghe, Cai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Pre-Clinical Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973069/ https://www.ncbi.nlm.nih.gov/pubmed/35350907 http://dx.doi.org/10.1177/03000605221088431

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