Serine/Threonine Protein Phosphatase 2A Regulates the Transport of Axonal Mitochondria

Microtubule-based transport provides mitochondria to distant regions of neurons and is essential for neuronal health. To identify compounds that increase mitochondrial motility, we screened 1,641 small-molecules in a high-throughput screening platform. Indirubin and cantharidin increased mitochondri...

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Detalles Bibliográficos
Autores principales: Heo, Keunjung, Basu, Himanish, Gutnick, Amos, Wei, Wei, Shlevkov, Evgeny, Schwarz, Thomas L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973303/
https://www.ncbi.nlm.nih.gov/pubmed/35370563
http://dx.doi.org/10.3389/fncel.2022.852245

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973303/
https://www.ncbi.nlm.nih.gov/pubmed/35370563
http://dx.doi.org/10.3389/fncel.2022.852245

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