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β-Hydroxyisovalerylshikonin regulates macrophage polarization via the AMPK/Nrf2 pathway and ameliorates sepsis in mice

CONTEXT: The potential anti-inflammatory bioactivities of β-hydroxyisovalerylshikonin (β-HIVS) remain largely unknown. OBJECTIVE: This study investigated the anti-inflammatory effects and underlying mechanisms of β-HIVS. MATERIALS AND METHODS: RAW 264.7 cells stimulated with LPS (100 ng/mL) for 24 h...

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Detalles Bibliográficos
Autores principales:	Pan, Tao, Chang, Yabin, He, Min, He, Zehui, Jiang, Jun, Ren, Xinling, Zhang, Fang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973340/ https://www.ncbi.nlm.nih.gov/pubmed/35352622 http://dx.doi.org/10.1080/13880209.2022.2046111

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