Discovery of novel sulphonamide hybrids that inhibit LSD1 against bladder cancer cells

Aim:A series of sulphonamide hybrids were designed, synthesised, and identified as potential lysine-specific demethylase 1 (LSD1) inhibitors. Materials and methods: Bladder cancer cell lines were cultured to evaluate the antiproliferative activity. Inhibitory evaluation of sulphonamide hybrids again...

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Detalles Bibliográficos
Autores principales: Liu, Jia, Zhu, Xingwang, Yu, Liu, Mao, Minghuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973347/
https://www.ncbi.nlm.nih.gov/pubmed/35350943
http://dx.doi.org/10.1080/14756366.2021.2014830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973347/
https://www.ncbi.nlm.nih.gov/pubmed/35350943
http://dx.doi.org/10.1080/14756366.2021.2014830

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