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Discovery of novel sulphonamide hybrids that inhibit LSD1 against bladder cancer cells
Aim:A series of sulphonamide hybrids were designed, synthesised, and identified as potential lysine-specific demethylase 1 (LSD1) inhibitors. Materials and methods: Bladder cancer cell lines were cultured to evaluate the antiproliferative activity. Inhibitory evaluation of sulphonamide hybrids again...
Autores principales: | Liu, Jia, Zhu, Xingwang, Yu, Liu, Mao, Minghuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973347/ https://www.ncbi.nlm.nih.gov/pubmed/35350943 http://dx.doi.org/10.1080/14756366.2021.2014830 |
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