4-Anilinoquinazoline-based benzenesulfonamides as nanomolar inhibitors of carbonic anhydrase isoforms I, II, IX, and XII: design, synthesis, in-vitro, and in-silico biological studies

Human carbonic anhydrase inhibitors (hCAIs) are a key therapeutic class with a multitude of novel applications such as anticonvulsants, topically acting antiglaucoma, and anticancer drugs. Herein, a new series of 4-anilinoquinazoline-based benzenesulfonamides were designed, synthesised, and biologic...

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Detalles Bibliográficos
Autores principales: Nada, Hossam, Elkamhawy, Ahmed, Abdellattif, Magda H., Angeli, Andrea, Lee, Chang Hoon, Supuran, Claudiu T., Lee, Kyeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973350/
https://www.ncbi.nlm.nih.gov/pubmed/35350942
http://dx.doi.org/10.1080/14756366.2022.2055553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973350/
https://www.ncbi.nlm.nih.gov/pubmed/35350942
http://dx.doi.org/10.1080/14756366.2022.2055553

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