Dynamic phenotypic heterogeneity and the evolution of multiple RNA subtypes in hepatocellular carcinoma: the PLANET study

Intra-tumor heterogeneity (ITH) is a key challenge in cancer treatment, but previous studies have focused mainly on the genomic alterations without exploring phenotypic (transcriptomic and immune) heterogeneity. Using one of the largest prospective surgical cohorts for hepatocellular carcinoma (HCC)...

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Detalles Bibliográficos
Autores principales: Zhai, Weiwei, Lai, Hannah, Kaya, Neslihan Arife, Chen, Jianbin, Yang, Hechuan, Lu, Bingxin, Lim, Jia Qi, Ma, Siming, Chew, Sin Chi, Chua, Khi Pin, Alvarez, Jacob Josiah Santiago, Chen, Pauline Jieqi, Chang, Mei Mei, Wu, Lingyan, Goh, Brian K P, Chung, Alexander Yaw-Fui, Chan, Chung Yip, Cheow, Peng Chung, Lee, Ser Yee, Kam, Juinn Huar, Kow, Alfred Wei-Chieh, Ganpathi, Iyer Shridhar, Chanwat, Rawisak, Thammasiri, Jidapa, Yoong, Boon Koon, Ong, Diana Bee-Lan, de Villa, Vanessa H, Dela Cruz, Rouchelle D, Loh, Tracy Jiezhen, Wan, Wei Keat, Zeng, Zeng, Skanderup, Anders Jacobsen, Pang, Yin Huei, Madhavan, Krishnakumar, Lim, Tony Kiat-Hon, Bonney, Glenn, Leow, Wei Qiang, Chew, Valerie, Dan, Yock Young, Tam, Wai Leong, Toh, Han Chong, Foo, Roger Sik-Yin, Chow, Pierce Kah-Hoe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
RESEARCH ARTICLE
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973408/
https://www.ncbi.nlm.nih.gov/pubmed/35382356
http://dx.doi.org/10.1093/nsr/nwab192

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