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Mini review: Prospective therapeutic targets of Alzheimer's disease
Alzheimer's disease is a neurological condition that causes the disruption of neuronal connections in the human brain. It is progressive and targets about 10% of the United States population over the age of 65.3 to date, there is no cure to the disease. Physicians can treat symptoms but lack th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973446/ https://www.ncbi.nlm.nih.gov/pubmed/35372728 http://dx.doi.org/10.4103/bc.bc_20_21 |
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author | Mangal, Ruchi Ding, Yuchuan |
author_facet | Mangal, Ruchi Ding, Yuchuan |
author_sort | Mangal, Ruchi |
collection | PubMed |
description | Alzheimer's disease is a neurological condition that causes the disruption of neuronal connections in the human brain. It is progressive and targets about 10% of the United States population over the age of 65.3 to date, there is no cure to the disease. Physicians can treat symptoms but lack the ability to stop the progression of the disease. However, promising research has come to the surface in recent years. A collection of these therapeutic targets, which have yielded positive results in mice models, are presented in this article. They include targets such as meningeal lymphatics, mitochondrial homeostasis, genomic instability, calcium homeostasis, and cold-shock proteins such as RNA-binding motif protein 3 and reticulon-3, high-density lipoprotein, and antibodies. |
format | Online Article Text |
id | pubmed-8973446 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-89734462022-04-02 Mini review: Prospective therapeutic targets of Alzheimer's disease Mangal, Ruchi Ding, Yuchuan Brain Circ Review Article Alzheimer's disease is a neurological condition that causes the disruption of neuronal connections in the human brain. It is progressive and targets about 10% of the United States population over the age of 65.3 to date, there is no cure to the disease. Physicians can treat symptoms but lack the ability to stop the progression of the disease. However, promising research has come to the surface in recent years. A collection of these therapeutic targets, which have yielded positive results in mice models, are presented in this article. They include targets such as meningeal lymphatics, mitochondrial homeostasis, genomic instability, calcium homeostasis, and cold-shock proteins such as RNA-binding motif protein 3 and reticulon-3, high-density lipoprotein, and antibodies. Wolters Kluwer - Medknow 2022-03-21 /pmc/articles/PMC8973446/ /pubmed/35372728 http://dx.doi.org/10.4103/bc.bc_20_21 Text en Copyright: © 2022 Brain Circulation https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Review Article Mangal, Ruchi Ding, Yuchuan Mini review: Prospective therapeutic targets of Alzheimer's disease |
title | Mini review: Prospective therapeutic targets of Alzheimer's disease |
title_full | Mini review: Prospective therapeutic targets of Alzheimer's disease |
title_fullStr | Mini review: Prospective therapeutic targets of Alzheimer's disease |
title_full_unstemmed | Mini review: Prospective therapeutic targets of Alzheimer's disease |
title_short | Mini review: Prospective therapeutic targets of Alzheimer's disease |
title_sort | mini review: prospective therapeutic targets of alzheimer's disease |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973446/ https://www.ncbi.nlm.nih.gov/pubmed/35372728 http://dx.doi.org/10.4103/bc.bc_20_21 |
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