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Emodin relieves the inflammation and pyroptosis of lipopolysaccharide-treated 1321N1 cells by regulating methyltransferase-like 3 -mediated NLR family pyrin domain containing 3 expression

Sepsis brain injury (SBI) is a major cause of death in critically ill patients. The present study aimed to investigate the role of emodin in SBI development. Human astrocyte 1321N1 cells were stimulated with 100 ng/mL lipopolysaccharide (LPS) to establish an SBI model in vitro. Flow cytometry was pe...

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Detalles Bibliográficos
Autores principales: Wang, Bu, Liu, Yuan, Jiang, Rui, Liu, Zhiliang, Gao, Haiyun, Chen, Fenqiao, Mei, Jianqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973593/
https://www.ncbi.nlm.nih.gov/pubmed/35246004
http://dx.doi.org/10.1080/21655979.2022.2045836

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