A peptide derived from the N-terminus of charged multivesicular body protein 6 (CHMP6) promotes the secretion of gene editing proteins via small extracellular vesicle production

Extracellular vesicles (EVs) are a promising new therapeutic platform. However, the low cargo-loading efficiency limits their clinical translation. In this study, we developed a high-yield EV cargo-loading device and explored its ability to encapsulate gene editing proteins. A series of fusion prote...

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Detalles Bibliográficos
Autores principales: Fan, Junyu, Pan, Jiajie, Zhang, Xiaozhe, Chen, Yixi, Zeng, Yue, Huang, Lihan, Ma, Dongwei, Chen, Ziqi, Wu, Guifu, Fan, Wendong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973635/
https://www.ncbi.nlm.nih.gov/pubmed/35188876
http://dx.doi.org/10.1080/21655979.2022.2030571

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