Plectin pulls it together, coupling the cortical actin and intermediate filament cytoskeletons

The integration of cytoskeletal/adhesive networks is critical to epithelial mechanobiology. In this issue, Prechova et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202105146) demonstrate that the cytolinker protein plectin is essential for the construction of a cortical cytoskeletal architec...

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Detalles Bibliográficos
Autores principales: Broussard, Joshua A., Green, Kathleen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Spotlight
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973661/
https://www.ncbi.nlm.nih.gov/pubmed/35175283
http://dx.doi.org/10.1083/jcb.202201054
Descripción
Sumario:The integration of cytoskeletal/adhesive networks is critical to epithelial mechanobiology. In this issue, Prechova et al. (2022. J. Cell Biol. https://doi.org/10.1083/jcb.202105146) demonstrate that the cytolinker protein plectin is essential for the construction of a cortical cytoskeletal architecture required for epithelial tensional homeostasis.

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