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Combination therapy of Ulinastatin with Thrombomodulin alleviates endotoxin (LPS) - induced liver and kidney injury via inhibiting apoptosis, oxidative stress and HMGB1/TLR4/NF-κB pathway

Sepsis is a type of systemic inflammation response syndrome that leads to organ function disorders. Currently, there is no specific medicine for sepsis in clinical practice. Lipopolysaccharide (LPS) is an important endotoxin that causes sepsis. Here, we report an effective two-drug combination thera...

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Detalles Bibliográficos
Autores principales: Zhang, Xiong, Su, Chenlin, Zhao, Shuxin, Li, Ji, Yu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973693/
https://www.ncbi.nlm.nih.gov/pubmed/35148668
http://dx.doi.org/10.1080/21655979.2021.2024686