Rapamycin ameliorates chronic intermittent hypoxia and sleep deprivation-induced renal damage via the mammalian target of rapamycin (mTOR)/NOD-like receptor protein 3 (NLRP3) signaling pathway

Rapamycin inhibits the activation of NOD-like receptor protein 3 (NLRP3) by regulating the mammalian target of rapamycin (mTOR) to treat obstructive sleep apnea-related renal injury. Sleep deprivation (SD) and chronic intermittent hypoxia (CIH) mouse models were used to assess the effects of autopha...

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Detalles Bibliográficos
Autores principales: Liu, Wei, Zhao, Dong, Wu, Xiaofeng, Yue, Fang, Yang, Haizhen, Hu, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973698/
https://www.ncbi.nlm.nih.gov/pubmed/35184679
http://dx.doi.org/10.1080/21655979.2022.2037872

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