The landscape of GWAS validation; systematic review identifying 309 validated non-coding variants across 130 human diseases

BACKGROUND: The remarkable growth of genome-wide association studies (GWAS) has created a critical need to experimentally validate the disease-associated variants, 90% of which involve non-coding variants. METHODS: To determine how the field is addressing this urgent need, we performed a comprehensi...

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Detalles Bibliográficos
Autores principales: Alsheikh, Ammar J., Wollenhaupt, Sabrina, King, Emily A., Reeb, Jonas, Ghosh, Sujana, Stolzenburg, Lindsay R., Tamim, Saleh, Lazar, Jozef, Davis, J. Wade, Jacob, Howard J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973751/
https://www.ncbi.nlm.nih.gov/pubmed/35365203
http://dx.doi.org/10.1186/s12920-022-01216-w

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