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Leucine rich alpha-2-glycoprotein 1 (Lrg1) silencing protects against sepsis-mediated brain injury by inhibiting transforming growth factor beta1 (TGFβ1)/SMAD signaling pathway

Sepsis-associated encephalopathy (SAE) is key manifestation of sepsis which is responsible for increased morbidity and mortality. Leucine rich alpha-2-glycoprotein 1 (Lrg1) is a secreted protein implicated in a variety of diseases. We aimed to explore the effects and potential mechanism of Lrg1 on s...

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Detalles Bibliográficos
Autores principales:	Miao, Youhan, Wang, Meihua, Cai, Xiaojuan, Zhu, Qiqi, Mao, Liping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973760/ https://www.ncbi.nlm.nih.gov/pubmed/35264055 http://dx.doi.org/10.1080/21655979.2022.2048775

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