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Hirudin promotes proliferation and osteogenic differentiation of HBMSCs via activation of cyclic guanosine monophosphate (cGMP)/protein kinase-G (PKG) signaling pathway

Osteoporosis is a public health problem resulting in higher susceptibility to bone fracture. Hirudin is known as a direct thrombin inhibitor, which is isolated from the salivary gland of the medicinal leech. The present study aimed to evaluate the effect of Hirudin on the proliferation and osteogeni...

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Detalles Bibliográficos
Autores principales: Cao, Shun, Li, Xianghui, Feng, Ting, Li, Yaqing, Ding, Hongwei, Xie, Lin, Yang, Quanhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973852/
https://www.ncbi.nlm.nih.gov/pubmed/34898364
http://dx.doi.org/10.1080/21655979.2021.2008697