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Hirudin promotes proliferation and osteogenic differentiation of HBMSCs via activation of cyclic guanosine monophosphate (cGMP)/protein kinase-G (PKG) signaling pathway
Osteoporosis is a public health problem resulting in higher susceptibility to bone fracture. Hirudin is known as a direct thrombin inhibitor, which is isolated from the salivary gland of the medicinal leech. The present study aimed to evaluate the effect of Hirudin on the proliferation and osteogeni...
Autores principales: | Cao, Shun, Li, Xianghui, Feng, Ting, Li, Yaqing, Ding, Hongwei, Xie, Lin, Yang, Quanhong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973852/ https://www.ncbi.nlm.nih.gov/pubmed/34898364 http://dx.doi.org/10.1080/21655979.2021.2008697 |
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