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Sulforaphane ameliorates amyloid-β-induced inflammatory injury by suppressing the PARP1/SIRT1 pathway in retinal pigment epithelial cells

Age-associated macular degeneration (AMD) is a progressive eye disorder that leads to irreversible impairment of central vision, and effective therapies are lacking. Here, we explore how oligomeric amyloid-β(1-42) can trigger inflammatory injury in retinal pigment epithelial cells and how sulforapha...

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Detalles Bibliográficos
Autores principales: Wang, Song, Tang, Yu-jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973853/
https://www.ncbi.nlm.nih.gov/pubmed/34982643
http://dx.doi.org/10.1080/21655979.2021.1976503