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Sulforaphane ameliorates amyloid-β-induced inflammatory injury by suppressing the PARP1/SIRT1 pathway in retinal pigment epithelial cells
Age-associated macular degeneration (AMD) is a progressive eye disorder that leads to irreversible impairment of central vision, and effective therapies are lacking. Here, we explore how oligomeric amyloid-β(1-42) can trigger inflammatory injury in retinal pigment epithelial cells and how sulforapha...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Taylor & Francis
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973853/ https://www.ncbi.nlm.nih.gov/pubmed/34982643 http://dx.doi.org/10.1080/21655979.2021.1976503 |