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Mechanistic Studies of Gypenosides in Microglial State Transition and its Implications in Depression-Like Behaviors: Role of TLR4/MyD88/NF-κB Signaling

Depression is a prevalent psychiatric disorder. Microglial state transition has been found in many neurological disorders including depression. Gypenosides (Gypenosides I-LXXVIII, Gps) are saponin extracts isolated from the traditional Chinese herb Gynostemma pentaphyllum (Thunb.) Makino that exert...

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Detalles Bibliográficos
Autores principales: Cao, Li-Hua, Zhao, Yuan-Yuan, Bai, Ming, Geliebter, David, Geliebter, Jan, Tiwari, Raj, He, Hong-Juan, Wang, Zhen-zhen, Jia, Xing-Yuan, Li, Jin, Li, Xiu-Min, Miao, Ming-San
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973912/
https://www.ncbi.nlm.nih.gov/pubmed/35370734
http://dx.doi.org/10.3389/fphar.2022.838261

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