Effects of Dimethyl Fumarate on Brain Atrophy in Relapsing-Remitting Multiple Sclerosis: Pooled Analysis Phase 3 DEFINE and CONFIRM Studies

OBJECTIVE: In the pivotal DEFINE and CONFIRM trials for dimethyl fumarate (DMF), patterns of brain volume changes were different, potentially due to low sample sizes and because MRIs were analyzed at two different reading centers. We evaluated effects of DMF on brain volume change in patients with m...

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Detalles Bibliográficos
Autores principales: Nakamura, Kunio, Mokliatchouk, Oksana, Arnold, Douglas L., Yousry, Tarek A., Kappos, Ludwig, Richert, Nancy, Ayling-Rouse, Katherine, Miller, Catherine, Fisher, Elizabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973916/
https://www.ncbi.nlm.nih.gov/pubmed/35370887
http://dx.doi.org/10.3389/fneur.2022.809273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973916/
https://www.ncbi.nlm.nih.gov/pubmed/35370887
http://dx.doi.org/10.3389/fneur.2022.809273

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