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Timosaponin B-II alleviates osteoarthritis-related inflammation and extracellular matrix degradation through inhibition of mitogen-activated protein kinases and nuclear factor-κB pathways in vitro

Osteoarthritis (OA), an inflammatory response in chondrocytes, leads to extracellular matrix (ECM) degradation and cartilage destruction. Timosaponin B-II (TB-II) is the main bioactive component of Rhizoma Anemarrhenae with reported antioxidant and anti-inflammatory effects. This study investigated...

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Detalles Bibliográficos
Autores principales: Liu, Xinwei, Xiang, Dulei, Jin, Wenming, Zhao, Gen, Li, Han, Xie, Bing, Gu, Xiaochuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973927/
https://www.ncbi.nlm.nih.gov/pubmed/35094658
http://dx.doi.org/10.1080/21655979.2021.2024685