Cargando…
Timosaponin B-II alleviates osteoarthritis-related inflammation and extracellular matrix degradation through inhibition of mitogen-activated protein kinases and nuclear factor-κB pathways in vitro
Osteoarthritis (OA), an inflammatory response in chondrocytes, leads to extracellular matrix (ECM) degradation and cartilage destruction. Timosaponin B-II (TB-II) is the main bioactive component of Rhizoma Anemarrhenae with reported antioxidant and anti-inflammatory effects. This study investigated...
Autores principales: | Liu, Xinwei, Xiang, Dulei, Jin, Wenming, Zhao, Gen, Li, Han, Xie, Bing, Gu, Xiaochuan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973927/ https://www.ncbi.nlm.nih.gov/pubmed/35094658 http://dx.doi.org/10.1080/21655979.2021.2024685 |
Ejemplares similares
-
STING promotes senescence, apoptosis, and extracellular matrix degradation in osteoarthritis via the NF-κB signaling pathway
por: Guo, Qiang, et al.
Publicado: (2021) -
Tongbi Huoluo Decoction alleviates cartilage degeneration in knee osteoarthritis by inhibiting degradation of extracellular matrix
por: Chen, Weijian, et al.
Publicado: (2023) -
Timosaponin B-II ameliorates diabetic nephropathy via TXNIP, mTOR, and NF-κB signaling pathways in alloxan-induced mice
por: Yuan, Yong-Liang, et al.
Publicado: (2015) -
Melatonin Prevents Chondrocyte Matrix Degradation in Rats with Experimentally Induced Osteoarthritis by Inhibiting Nuclear Factor-κB via SIRT1
por: Zhao, Mingchao, et al.
Publicado: (2022) -
The Nrf2/HMGB1/NF-κB axis modulates chondrocyte apoptosis and extracellular matrix degradation in osteoarthritis: Nrf2/HMGB1 affects osteoarthritis
por: Li, Wenzhao, et al.
Publicado: (2023)