Trimetazidine inhibits liver fibrosis and hepatic stellate cell proliferation and blocks transforming growth factor-β (TGFβ)/Smad signaling in vitro and in vivo

Trimetazidine (TMZ) has been used extensively to treat coronary artery disease and to reduce fibrosis. Liver fibrosis is a reversible process. However, the impacts of TMZ on liver fibrosis triggered by CCl(4) and on hepatic stellate cells in liver fibrosis remain to be elaborated. In the current stu...

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Detalles Bibliográficos
Autores principales: Ding, Wenwen, Zhou, Danhua, Zhang, Shimeng, Qian, Jiaping, Yang, Lingxia, Tang, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8973947/
https://www.ncbi.nlm.nih.gov/pubmed/35249457
http://dx.doi.org/10.1080/21655979.2022.2047403

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