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An inhibitory effect on the nuclear accumulation of phospho-STAT1 by its unphosphorylated form

BACKGROUND: Unphosphorylated signal transducer and activator of transcription 1 (U-STAT1) has been reported to elicit a distinct gene expression profile as compared to tyrosine-phosphorylated STAT1 (P-STAT1) homodimers. However, the impact of U-STAT1 on the IFNγ-induced immune response mediated by P...

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Detalles Bibliográficos
Autores principales:	Menon, Priyanka Rajeev, Staab, Julia, Gregus, Anke, Wirths, Oliver, Meyer, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974011/ https://www.ncbi.nlm.nih.gov/pubmed/35361236 http://dx.doi.org/10.1186/s12964-022-00841-3

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