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Melatonin affects hypoxia-inducible factor 1α and ameliorates delayed brain injury following subarachnoid hemorrhage via H19/miR-675/HIF1A/TLR4

This study aimed to investigate the molecular mechanism of how melatonin (MT) interferes with hypoxia-inducible factor 1α (HIF1A) and toll-like receptor 4 (TLR4) expression, which is implicated in the management of delayed brain injury (DBI) after subarachnoid hemorrhage (SAH). Luciferase assay, rea...

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Detalles Bibliográficos
Autores principales: Xu, Zhijian, Zhang, Fengduo, Xu, Hu, Yang, Fan, Zhou, Gezhi, Tong, Minfeng, Li, Yaqiang, Yang, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974079/
https://www.ncbi.nlm.nih.gov/pubmed/35170388
http://dx.doi.org/10.1080/21655979.2022.2027175

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