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Melatonin affects hypoxia-inducible factor 1α and ameliorates delayed brain injury following subarachnoid hemorrhage via H19/miR-675/HIF1A/TLR4
This study aimed to investigate the molecular mechanism of how melatonin (MT) interferes with hypoxia-inducible factor 1α (HIF1A) and toll-like receptor 4 (TLR4) expression, which is implicated in the management of delayed brain injury (DBI) after subarachnoid hemorrhage (SAH). Luciferase assay, rea...
Autores principales: | Xu, Zhijian, Zhang, Fengduo, Xu, Hu, Yang, Fan, Zhou, Gezhi, Tong, Minfeng, Li, Yaqiang, Yang, Song |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974079/ https://www.ncbi.nlm.nih.gov/pubmed/35170388 http://dx.doi.org/10.1080/21655979.2022.2027175 |
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