A versatile transposon-based technology to generate loss- and gain-of-function phenotypes in the mouse liver

BACKGROUND: Understanding the contribution of gene function in distinct organ systems to the pathogenesis of human diseases in biomedical research requires modifying gene expression through the generation of gain- and loss-of-function phenotypes in model organisms, for instance, the mouse. However,...

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Detalles Bibliográficos
Autores principales: Kopasz, Anna Georgina, Pusztai, Dávid Zsolt, Karkas, Réka, Hudoba, Liza, Abdullah, Khaldoon Sadiq Ahmed, Imre, Gergely, Pankotai-Bodó, Gabriella, Migh, Ede, Nagy, Andrea, Kriston, András, Germán, Péter, Drubi, Andrea Bakné, Molnár, Anna, Fekete, Ildikó, Dani, Virág Éva, Ocsovszki, Imre, Puskás, László Géza, Horváth, Péter, Sükösd, Farkas, Mátés, Lajos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974095/
https://www.ncbi.nlm.nih.gov/pubmed/35361222
http://dx.doi.org/10.1186/s12915-022-01262-x

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