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Novel protein kinase C phosphorylated kinase inhibitor-matrine suppresses replication of hepatitis B virus via modulating the mitogen-activated protein kinase signal

HBV (hepatitis B virus) infection still threatens human health. Therefore, it is essential to find new effective anti-HBV compounds. Here, we identified matrine as a novel inhibitor of PKC (protein kinase C) phosphorylated kinase by screening a natural compound library. After HepG2.215 cells were tr...

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Detalles Bibliográficos
Autores principales:	Zhou, Shen, Li, Yuan, Gao, Jing, Wang, Yanyan, Ma, Xinping, Ding, Hui, Li, Xiuling, Sun, Suofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974119/ https://www.ncbi.nlm.nih.gov/pubmed/35037840 http://dx.doi.org/10.1080/21655979.2021.2024957

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