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Trimetazidine mitigates high glucose-induced retinal endothelial dysfunction by inhibiting PI3K/Akt/mTOR pathway-mediated autophagy

Trimetazidine (TMZ), as a metabolic regulator, has been widely testified to exhibit positive therapeutic effects on various disease models, but its role in diabetic retinopathy has not been reported. Therefore, this study was designed with the purpose of exploring the effects of TMZ on high-glucose...

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Detalles Bibliográficos
Autores principales: Yang, Qingsong, Li, Sizhen, Zhou, Zixiu, Yang, Xiaodong, Liu, Yating, Hao, Kuanxiao, Fu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974130/
https://www.ncbi.nlm.nih.gov/pubmed/35259050
http://dx.doi.org/10.1080/21655979.2022.2048993

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