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Downregulation of sperm-associated antigen 5 inhibits melanoma progression by regulating forkhead box protein M1/A disintegrin and metalloproteinase 17/NOTCH1 signaling

Sperm-associated antigen 5 (SPAG5) has been identified as a driver in several type of cancers. In this study, we aimed to reveal the role of SPAG5 in melanoma and clarify whether FOXM1 (forkhead box protein M1) /ADAM17 (A disintegrin and metalloproteinase 17) /NOTCH1 signaling was involved. The expr...

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Detalles Bibliográficos
Autores principales: Dang, Lin, Shi, Cuiping, Zhang, Qianqian, Liao, Peiyu, Wang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974132/
https://www.ncbi.nlm.nih.gov/pubmed/35138218
http://dx.doi.org/10.1080/21655979.2022.2031670