Hurdles to breakthrough in CAR T cell therapy of solid tumors

Autologous T cells genetically engineered to express chimeric antigen receptor (CAR) have shown promising outcomes and emerged as a new curative option for hematological malignancy, especially malignant neoplasm of B cells. Notably, when T cells are transduced with CAR constructs, composed of the an...

Descripción completa

Detalles Bibliográficos
Autores principales: Marofi, Faroogh, Achmad, Harun, Bokov, Dmitry, Abdelbasset, Walid Kamal, Alsadoon, Zeid, Chupradit, Supat, Suksatan, Wanich, Shariatzadeh, Siavash, Hasanpoor, Zahra, Yazdanifar, Mahboubeh, Shomali, Navid, Khiavi, Farhad Motavalli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974159/
https://www.ncbi.nlm.nih.gov/pubmed/35365241
http://dx.doi.org/10.1186/s13287-022-02819-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974159/
https://www.ncbi.nlm.nih.gov/pubmed/35365241
http://dx.doi.org/10.1186/s13287-022-02819-x

Ejemplares similares