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Hurdles to breakthrough in CAR T cell therapy of solid tumors

Autologous T cells genetically engineered to express chimeric antigen receptor (CAR) have shown promising outcomes and emerged as a new curative option for hematological malignancy, especially malignant neoplasm of B cells. Notably, when T cells are transduced with CAR constructs, composed of the an...

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Detalles Bibliográficos
Autores principales:	Marofi, Faroogh, Achmad, Harun, Bokov, Dmitry, Abdelbasset, Walid Kamal, Alsadoon, Zeid, Chupradit, Supat, Suksatan, Wanich, Shariatzadeh, Siavash, Hasanpoor, Zahra, Yazdanifar, Mahboubeh, Shomali, Navid, Khiavi, Farhad Motavalli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974159/ https://www.ncbi.nlm.nih.gov/pubmed/35365241 http://dx.doi.org/10.1186/s13287-022-02819-x

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