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TP53 R273C Mutation Is Associated With Poor Prognosis in LGG Patients

Purpose: With the progress of cancer immunotherapy, hotspot mutations of common oncogenes and tumor suppressors are becoming new potential therapeutic targets. TP53 R273C mutation is one of the hotspot mutations of TP53, and it has a higher frequency in low-grade glioma (LGG). However, the function...

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Detalles Bibliográficos
Autores principales:	Zhang, Jian, Liu, Minglu, Fang, Yujie, Li, Jinlong, Chen, Yin, Jiao, Shunchang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Genetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974296/ https://www.ncbi.nlm.nih.gov/pubmed/35368662 http://dx.doi.org/10.3389/fgene.2022.720651

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