Clinical Validity of Plasma-Based Genotyping for Microsatellite Instability Assessment in Advanced GI Cancers: SCRUM-Japan GOZILA Substudy

PURPOSE: Circulating tumor DNA (ctDNA) genotyping may guide targeted therapy for patients with advanced GI cancers. However, no studies have validated ctDNA genotyping for microsatellite instability (MSI) assessment in comparison with a tissue-based standard. PATIENTS AND METHODS: The performance of...

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Detalles Bibliográficos
Autores principales: Nakamura, Yoshiaki, Okamoto, Wataru, Denda, Tadamichi, Nishina, Tomohiro, Komatsu, Yoshito, Yuki, Satoshi, Yasui, Hisateru, Esaki, Taito, Sunakawa, Yu, Ueno, Makoto, Shinozaki, Eiji, Matsuhashi, Nobuhisa, Ohta, Takashi, Kato, Ken, Ohtsubo, Koushiro, Bando, Hideaki, Hara, Hiroki, Satoh, Taroh, Yamazaki, Kentaro, Yamamoto, Yoshiyuki, Okano, Naohiro, Terazawa, Tetsuji, Kato, Takeshi, Oki, Eiji, Tsuji, Akihito, Horita, Yosuke, Hamamoto, Yasuo, Kawazoe, Akihito, Nakajima, Hiromichi, Nomura, Shogo, Mitani, Ryuta, Yuasa, Mihoko, Akagi, Kiwamu, Yoshino, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2022
Materias:
Original Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974570/
https://www.ncbi.nlm.nih.gov/pubmed/35188805
http://dx.doi.org/10.1200/PO.21.00383

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