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Human Lung Mast Cells Impair Corticosteroid Responsiveness in Human Airway Smooth Muscle Cells

The mechanisms underlying corticosteroid insensitivity in severe asthma have not been elucidated although some indirect clinical evidence points toward a role of mast cells. Here, we tested the hypothesis that mast cells can drive corticosteroid insensitivity in airway smooth muscle cells, a key pla...

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Detalles Bibliográficos
Autores principales:	Alzahrani, Abdulrahman, Hakeem, Jameel, Biddle, Michael, Alhadian, Fahad, Hussain, Aamir, Khalfaoui, Latifa, Roach, Katy M., Tliba, Omar, Bradding, Peter, Amrani, Yassine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Allergy
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974721/ https://www.ncbi.nlm.nih.gov/pubmed/35387008 http://dx.doi.org/10.3389/falgy.2021.785100

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