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The Nose as a Route for Therapy: Part 1. Pharmacotherapy
This article reviews nasal structure and function in the light of intranasal pharmacotherapy. The nose provides an accessible, fast route for local treatment of nose and sinus diseases, with lower doses than are necessary systemically and few adverse effects. It can also be used for other medication...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974766/ https://www.ncbi.nlm.nih.gov/pubmed/35387039 http://dx.doi.org/10.3389/falgy.2021.638136 |
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author | Cingi, Cemal Bayar Muluk, Nuray Mitsias, Dimitrios I. Papadopoulos, Nikolaos G. Klimek, Ludger Laulajainen-Hongisto, Anu Hytönen, Maija Toppila-Salmi, Sanna Katriina Scadding, Glenis Kathleen |
author_facet | Cingi, Cemal Bayar Muluk, Nuray Mitsias, Dimitrios I. Papadopoulos, Nikolaos G. Klimek, Ludger Laulajainen-Hongisto, Anu Hytönen, Maija Toppila-Salmi, Sanna Katriina Scadding, Glenis Kathleen |
author_sort | Cingi, Cemal |
collection | PubMed |
description | This article reviews nasal structure and function in the light of intranasal pharmacotherapy. The nose provides an accessible, fast route for local treatment of nose and sinus diseases, with lower doses than are necessary systemically and few adverse effects. It can also be used for other medications as it has sufficient surface area protected from local damage by mucociliary clearance, absence of digestive enzymes, responsive blood flow, and provides a rapid route to the central nervous system. |
format | Online Article Text |
id | pubmed-8974766 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-89747662022-04-05 The Nose as a Route for Therapy: Part 1. Pharmacotherapy Cingi, Cemal Bayar Muluk, Nuray Mitsias, Dimitrios I. Papadopoulos, Nikolaos G. Klimek, Ludger Laulajainen-Hongisto, Anu Hytönen, Maija Toppila-Salmi, Sanna Katriina Scadding, Glenis Kathleen Front Allergy Allergy This article reviews nasal structure and function in the light of intranasal pharmacotherapy. The nose provides an accessible, fast route for local treatment of nose and sinus diseases, with lower doses than are necessary systemically and few adverse effects. It can also be used for other medications as it has sufficient surface area protected from local damage by mucociliary clearance, absence of digestive enzymes, responsive blood flow, and provides a rapid route to the central nervous system. Frontiers Media S.A. 2021-02-22 /pmc/articles/PMC8974766/ /pubmed/35387039 http://dx.doi.org/10.3389/falgy.2021.638136 Text en Copyright © 2021 Cingi, Bayar Muluk, Mitsias, Papadopoulos, Klimek, Laulajainen-Hongisto, Hytönen, Toppila-Salmi and Scadding. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Allergy Cingi, Cemal Bayar Muluk, Nuray Mitsias, Dimitrios I. Papadopoulos, Nikolaos G. Klimek, Ludger Laulajainen-Hongisto, Anu Hytönen, Maija Toppila-Salmi, Sanna Katriina Scadding, Glenis Kathleen The Nose as a Route for Therapy: Part 1. Pharmacotherapy |
title | The Nose as a Route for Therapy: Part 1. Pharmacotherapy |
title_full | The Nose as a Route for Therapy: Part 1. Pharmacotherapy |
title_fullStr | The Nose as a Route for Therapy: Part 1. Pharmacotherapy |
title_full_unstemmed | The Nose as a Route for Therapy: Part 1. Pharmacotherapy |
title_short | The Nose as a Route for Therapy: Part 1. Pharmacotherapy |
title_sort | nose as a route for therapy: part 1. pharmacotherapy |
topic | Allergy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974766/ https://www.ncbi.nlm.nih.gov/pubmed/35387039 http://dx.doi.org/10.3389/falgy.2021.638136 |
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