Vaginal and Extra-Vaginal Bacterial Colonization and Risk for Incident Bacterial Vaginosis in a Population of Women Who Have Sex With Men

BACKGROUND: Bacterial vaginosis (BV) is a common cause of vaginal discharge and associated with vaginal acquisition of BV-associated bacteria (BVAB). METHODS: We used quantitative polymerase chain reaction assays to determine whether presence or concentrations of BVAB in the mouth, anus, vagina, or...

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Autores principales: Fredricks, David N, Plantinga, Anna, Srinivasan, Sujatha, Oot, Antoinette, Wiser, Andrew, Fiedler, Tina L, Proll, Sean, Wu, Michael C, Marrazzo, Jeanne M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Major Articles and Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974833/
https://www.ncbi.nlm.nih.gov/pubmed/32379324
http://dx.doi.org/10.1093/infdis/jiaa233
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author Fredricks, David N
Plantinga, Anna
Srinivasan, Sujatha
Oot, Antoinette
Wiser, Andrew
Fiedler, Tina L
Proll, Sean
Wu, Michael C
Marrazzo, Jeanne M
author_facet Fredricks, David N
Plantinga, Anna
Srinivasan, Sujatha
Oot, Antoinette
Wiser, Andrew
Fiedler, Tina L
Proll, Sean
Wu, Michael C
Marrazzo, Jeanne M
author_sort Fredricks, David N
collection PubMed
description BACKGROUND: Bacterial vaginosis (BV) is a common cause of vaginal discharge and associated with vaginal acquisition of BV-associated bacteria (BVAB). METHODS: We used quantitative polymerase chain reaction assays to determine whether presence or concentrations of BVAB in the mouth, anus, vagina, or labia before BV predict risk of incident BV in 72 women who have sex with men. RESULTS: Baseline vaginal and extra-vaginal colonization with Gardnerella spp, Megasphaera spp, Sneathia spp, BVAB-2, Dialister sp type 2, and other BVAB was more common among subjects with incident BV. CONCLUSIONS: Prior colonization with BVAB is a consistent risk for BV.
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spelling pubmed-89748332022-04-04 Vaginal and Extra-Vaginal Bacterial Colonization and Risk for Incident Bacterial Vaginosis in a Population of Women Who Have Sex With Men Fredricks, David N Plantinga, Anna Srinivasan, Sujatha Oot, Antoinette Wiser, Andrew Fiedler, Tina L Proll, Sean Wu, Michael C Marrazzo, Jeanne M J Infect Dis Major Articles and Brief Reports BACKGROUND: Bacterial vaginosis (BV) is a common cause of vaginal discharge and associated with vaginal acquisition of BV-associated bacteria (BVAB). METHODS: We used quantitative polymerase chain reaction assays to determine whether presence or concentrations of BVAB in the mouth, anus, vagina, or labia before BV predict risk of incident BV in 72 women who have sex with men. RESULTS: Baseline vaginal and extra-vaginal colonization with Gardnerella spp, Megasphaera spp, Sneathia spp, BVAB-2, Dialister sp type 2, and other BVAB was more common among subjects with incident BV. CONCLUSIONS: Prior colonization with BVAB is a consistent risk for BV. Oxford University Press 2020-05-07 /pmc/articles/PMC8974833/ /pubmed/32379324 http://dx.doi.org/10.1093/infdis/jiaa233 Text en © The Author(s) 2020. Published by Oxford University Press for the Infectious Diseases Society of America. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (https://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Major Articles and Brief Reports
Fredricks, David N
Plantinga, Anna
Srinivasan, Sujatha
Oot, Antoinette
Wiser, Andrew
Fiedler, Tina L
Proll, Sean
Wu, Michael C
Marrazzo, Jeanne M
Vaginal and Extra-Vaginal Bacterial Colonization and Risk for Incident Bacterial Vaginosis in a Population of Women Who Have Sex With Men
title Vaginal and Extra-Vaginal Bacterial Colonization and Risk for Incident Bacterial Vaginosis in a Population of Women Who Have Sex With Men
title_full Vaginal and Extra-Vaginal Bacterial Colonization and Risk for Incident Bacterial Vaginosis in a Population of Women Who Have Sex With Men
title_fullStr Vaginal and Extra-Vaginal Bacterial Colonization and Risk for Incident Bacterial Vaginosis in a Population of Women Who Have Sex With Men
title_full_unstemmed Vaginal and Extra-Vaginal Bacterial Colonization and Risk for Incident Bacterial Vaginosis in a Population of Women Who Have Sex With Men
title_short Vaginal and Extra-Vaginal Bacterial Colonization and Risk for Incident Bacterial Vaginosis in a Population of Women Who Have Sex With Men
title_sort vaginal and extra-vaginal bacterial colonization and risk for incident bacterial vaginosis in a population of women who have sex with men
topic Major Articles and Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974833/
https://www.ncbi.nlm.nih.gov/pubmed/32379324
http://dx.doi.org/10.1093/infdis/jiaa233
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