DNAH2 facilitates the homologous recombination repair of Fanconi anemia pathway through modulating FANCD2 ubiquitination

Fanconi anemia (FA), an X-linked genetic or autosomal recessive disease, exhibits complicated pathogenesis. Previously, we detected the mutated Dynein Axonemal Heavy Chain 2 (DNAH2) gene in 2 FA cases. Herein, we further investigated the potential association between DNAH2 and the homologous recombi...

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Detalles Bibliográficos
Autores principales: Chang, Lixian, Gao, Xingjie, Wang, Yuxia, Huang, Chunmin, Gao, Min, Wang, Xiaomin, Liu, Chao, Wu, Wenqi, An, Wenbin, Wan, Yang, Zhang, Aoli, Zhang, Yingchi, Yuan, Weiping, Zhu, Xiaofan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8974987/
https://www.ncbi.nlm.nih.gov/pubmed/35402838
http://dx.doi.org/10.1097/BS9.0000000000000076

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