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GSDME maintains hematopoietic stem cells by balancing pyroptosis and apoptosis

GSDME contains a pore-forming domain at its N-terminal region to execute pyroptosis. Our previous study has reported that forced expression of Gsdme impairs the reconstitution capacity of hematopoietic stem cells (HSCs). While, how GSDME-mediated pyroptosis regulates HSCs remains unknown. Here, we s...

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Detalles Bibliográficos
Autores principales:	Yang, Xiuxiu, Cong, Tingting, He, Hanqing, Wang, Jianwei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8975053/ https://www.ncbi.nlm.nih.gov/pubmed/35402833 http://dx.doi.org/10.1097/BS9.0000000000000064

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